The Regulatory Effect of D-Alloxan on Glucose Metabolism and Lipid Metabolism in Diabetic Mice
نویسندگان
چکیده
To investigate the regulatory effect of d-alloxan on glucose metabolism and lipid in diabetic mice. Twenty five mice were divided into control group, fructose group cellulose group. The results showed that blood each reached peak at 90 min concentration was significantly lower than other groups (p<0.05). higher before after meal (p<0.05), liver glycogen insulin level groups, but difference not significant (p>0.05), muscle (p>0.05). triglyceride While it (p>0.05) there no total cholesterol between free fatty acid Compared with low density lipoprotein four (p<0.05) them content succinate dehydrogenase tissues hepatic lipase Alloxan can effectively regulate concentration, inhibit postprandial rise, improve level, has glycogen. It be used as an ideal substitute sucrose once disorder is improved, ability fat increased antioxidation function improved.
منابع مشابه
The effect of adropin on lipid and glucose metabolism in rats with hyperlipidemia
Objective(s):The aim of this study was to evaluate, for the first time, whether the effects of low-dose adropin administration is effective in rats with hyperlipidemia. Materials and Methods: Twenty one Wistar albino female rats were randomly divided into 3 groups and fed with high-fat diet for 4 weeks to establish the hyperlipidemia model. Meanwhile, adropin was administrated intraperitonealy...
متن کاملThe Splenectomy Effects on Lipid Profile and Glucose Metabolism in the Major Thalassemia Patients
Background: Splenectomy is a common treatment for beta thalassemia. It not only eliminates many complications by reducing the need for blood transfusion, but also causes new complications that threaten the patientschr('39') health. The aim of this study was to determine if splenectomy could alter the lipid profile and glucose metabolism in beta thalassemia major patients. Methods: In this case-...
متن کاملThe total flavonoids from Selaginella tamariscina (beauv.) Spring improve glucose and lipid metabolism in db/db mice
Objective(s): This study aimed to investigate the glucose and lipid metabolism improving effect of the total flavonoids from Selaginella tamariscina (Beauv.) Spring (TFST) on db/db mice, and to study its mechanism of action.Materials and Methods: The db/db mice were divided into 5 groups: the normal group (NC), the diabetic group (DM), t...
متن کاملthe effect of adropin on lipid and glucose metabolism in rats with hyperlipidemia
objective(s):the aim of this study was to evaluate, for the first time, whether the effects of low-dose adropin administration is effective in rats with hyperlipidemia. materials and methods: twenty one wistar albino female rats were randomly divided into 3 groups and fed with high-fat diet for 4 weeks to establish the hyperlipidemia model. meanwhile, adropin was administrated intraperitonealy ...
متن کاملEffect of nano-magnesium oxide on glucose concentration and lipid profile in diabetic laboratory mice
Nano-sized drugs have better distribution than their identical forms. Magnesium is the cofactor of various enzymes in lipid and glucose metabolism. In this study the effect of nano-magnesium oxide (nano-MgO) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. Mice were divided randomly into three equal groups (control, treatment and placebo)....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2022
ISSN: ['0250-474X', '1998-3743']
DOI: https://doi.org/10.36468/pharmaceutical-sciences.1003